The bi-allelic AdHu5 vaccine construct tended to induce stronger responses against the common, 3D7 and FVO pools in comparison to the equivalent AdHu5 mono-allelic regime (comparing groups B and C) but this did not reach statistical significance.
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Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1.
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