Barely Significant
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Klotho depletion contributes to increased inflammation in kidney of the db/db mouse model of diabetes via RelA (serine)536 phosphorylation.

Diabetes · 2011 · PMC3121423 · PMID 21593200

1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

did not reach statistical significanceP = 0.08so close (0.05 < p ≤ 0.1)
Although Klotho overexpression significantly reduced IL-8 in both culture media and cell lysates, MCP-1 production was significantly reduced only in culture media and did not reach statistical significance in cell lysates ( P = 0.08).

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