Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions.

PLoS Genet · 2011 · PMC3121749 · PMID 21731500

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a clear trendno p-value reported

In all 3 conditions, a clear trend emerges suggesting that more pSmad2 binding drives higher levels of gene expression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.