RASSF1 hypermethylation approached significance but did not meet our multiple comparisons cut-off in the AIS to adenocarcinoma comparison.
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DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.
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The sentences
The CDKN2A ex2 primer/probe set detects highly significant hypermethylation in a CpG island in exon 2 of CDKN2A in lung adenocarcinoma vs. adjacent non-tumor lung, showing more highly significant differences than probes for upstream CpG islands [36] .