Ultrastructural changes of the intracellular surfactant pool in a rat model of lung transplantation-related events.

Although the total volume of all Lb per lung taken together did not differ between control and I/R groups, there was a clear trend towards a decline of the total volume of Lb per AE2 cell.

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Considering the volume-to-surface ratio of Lb as a measure of the mean "thickness" of Lb, a highly significant correlation could be recognized with the total intubation time following clinical lung transplantation; the higher the volume-to-surface ratio of Lb in the contralateral lung was, the longer the post-operative intubation time [ 26 ].

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