Barely Significant
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On the representability of complete genomes by multiple competing finite-context (Markov) models.

PLoS One · 2011 · PMC3128062 · PMID 21738720

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quite significantno p-value reported
Moreover, even in the higher species, the capability of the Markov-only approach seems to be quite significant, since it is able to represent, at least, about 95% of the information of the genome.

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