Prognostic significance of the FLT3 ITD mutation in patients with normal-karyotype acute myeloid leukemia in relapse.

Korean J Hematol · 2011 · PMC3128906 · PMID 21747880

Europe PMC DOI

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0.1730

closest p · 3.5× alpha

0.1730

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showed a trendP =0.173not close (p > 0.1)

Comparison of prognosis in patients without FLT3 ITD mutation stratified by NPM1 genotype status at diagnosis and relapse Patients with NPM1 mutation at diagnosis showed a trend towards a better outcome, such as longer OS (24.6 vs. 17.3 months; P =0.173) and duration of CR (10.0 vs. 7.5 months; P =0.558) than those without NPM1 mutation at diagnosis.

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