End-of-study safety, immunogenicity, and efficacy of quadrivalent HPV (types 6, 11, 16, 18) recombinant vaccine in adult women 24-45 years of age.

Br J Cancer · 2011 · PMC3137403 · PMID 21629249

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did not reach statistical significanceno p-value reported

Efficacy against any grade CIN related to vaccine HPV types was statistically significant for all three analysis populations; however, efficacy estimates for CIN 2/3 or worse in the PPE, NRT, and ITT analysis populations did not reach statistical significance.

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