Other differences with borderline significance in the CCR5 Δ32/wt genotype distribution included transmission route (16.1%, 11.8%, and 14.2% for homosexual, heterosexual and injection drug use (IDU) related transmissions, respectively, p = 0.07), female vs. male gender (9.7% and 15.7%, respectively, p = 0.08) and initiation of antiretroviral treatment (20.0% among treatment naive individuals vs. 13.0% among cART treated patients, p = 0.09).
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Risk of all-cause mortality in HIV infected patients is associated with clinical, immunologic predictors and the CCR5 Δ32 deletion.
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The sentences
The near-significant difference between the male and female gender frequency might be related to the transmission route – higher number of women was infected sexually.