Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults.

Nutr Metab (Lond) · 2011 · PMC3143920 · PMID 21736725

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closest p · 2.0× alpha

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did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

Importantly, the GIR was inversely associated with plasma CDCA (r = -0.36, p = 0.05 for Center 1 ; r = -0.44, p = 0.03 for Center 2 ) and CA (r = -0.38, p = 0.04 for Center 1 ; r = -0.65, p = 0.001 for Center 2 ) levels; while the negative correlation with the DCA did not reach statistical significance (r = -0.30, p = 0.10 for Center 1 ; r = -0.35, p = 0.08 for Center 2 ) (Figure 1A-B ).

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