Adenovirus-vectored drug-vaccine duo as a rapid-response tool for conferring seamless protection against influenza.

Although several regimens protected mice against influenza-mediated mortality, the AdE double-dose regimen tended to confer more solid protection than its single-dose (day -47 or -2) counterpart as shown by less body weight loss after PR8 challenge even though the difference did not reach statistical significance ( Fig. 3 ).

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