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Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis.

J Neuroinflammation · 2011 · PMC3146845 · PMID 21711557

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Pegfilgrastim treatment decreased the expression of TNFα (to 19 ± 11 fold of wt) but interestingly, increased the expression of iNOS (to 0.8 ± 0.4 fold of wt), altering the inflammatory status closer to the wt situation, although these changes did not reach statistical significance.

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