Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells.

In recent studies, we have found that 20 S is the most potent naturally occurring osteogenic oxysterol in our M2 cell system and that the osteogenic effects of 5 μM 20 S used alone are quite significant, although less than those of 20 S + 22 S combination (data not shown).

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