Mast cells are critical for protection against peptic ulcers induced by the NSAID piroxicam.

PLoS One · 2011 · PMC3155563 · PMID 21858200

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showed a trendno p-value reported

In a separate study, treatment of WT mice with the histamine H1-receptor antagonist hydroxyzine hydrochloride at 40 μg/ml in drinking water prior to and during piroxicam exposure also showed a trend toward increased ulcer incidence (60%; n = 10).

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