Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial.

Diabetes Care · 2011 · PMC3161301 · PMID 21775755

Europe PMC DOI

hedged sentence

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

reached borderline significanceP = 0.074so close (0.05 < p ≤ 0.1)

After 4 years, NIS improved significantly on ALA and worsened on placebo ( P = 0.028) while the differences from baseline between the groups reached borderline significance for the pinprick test of NIS ( P = 0.074) and NIS-LL ( P = 0.0505).

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