Barely Significant
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Clinical pharmacokinetics of ketoprofen enantiomers in wild type of Cyp 2c8 and Cyp 2c9 patients with rheumatoid arthritis.

Eur J Drug Metab Pharmacokinet · 2011 · PMC3168450 · PMID 21516380

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quite significantno p-value reported
Though RA patients represented the same wild genotype, quite significant variabilities (Cl (−)- R = 2.37–13.50 L/h and Cl (+)- S = 2.44–9.90 L/h) existed in the pharmacokinetics parameters of KTP.

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