A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22.

Br J Cancer · 2011 · PMC3171011 · PMID 21811255

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borderline significantno p-value reported

In addition, rs11466445 in TGFBR1 , although being borderline significant in EPICOLON phase 1, was not genotyped in phase 2 because of incompatibility with the used high-throughput technology.

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did not reach statistical significanceno p-value reported

Our results in the first phase showed a borderline significant association (unadjusted P -value =0.0491, dominant inheritance) but did not reach statistical significance after multiple-testing correction, suggesting that rs11466445 does not increase CRC risk.

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