SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans.

PLoS One · 2011 · PMC3174146 · PMID 21935377

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

tended towards significancep = 0.054so close (0.05 < p ≤ 0.1)

One exception was the 3 h post-dose sample for subject 5, where the decrease in HIV-1 inhibition observed in the presence of seminal plasma tended towards significance (p = 0.054, n = 3, Wilcoxon signed-rank test) and was minimal in the context of this type of biological assay (average decrease of 4.5%) ( Figure 4C ).

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