Diagnosis and management of pulmonary arterial hypertension.

Pulm Med · 2011 · PMC3176617 · PMID 21941650

Europe PMC DOI

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did not reach statistical significanceno p-value reported

The improvement in cardiac index also exhibited a dose response relationship although the improvement in the 20 mg group compared with placebo did not reach statistical significance.

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a nonsignificant trendno p-value reported

There was a nonsignificant trend towards further improvement with the 250 mg dose as compared to 125 mg.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.