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Growth hormone mediates pubertal skeletal development independent of hepatic IGF-1 production.

J Bone Miner Res · 2011 · PMC3179330 · PMID 20928887

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Tt.Ar values also were reduced in both strains, but the reduction did not reach statistical significance in the control mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.