Previous studies showed a trend toward decreasing familial risk schizophrenia with increasing age at onset. 35 Some reports have suggested the existence of a subgroup of affected females with late onset and no family history of schizophrenia. 57 , 58 In addition, later-onset illness is associated with clinical peculiarities (intensity of delusions and presence of multiple-sense hallucinations, rarity of negative symptoms, or thought disorder) and a better outcome.
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The French concept of "psychose hallucinatoire chronique" -a preliminary form of schizophrenia? The role of late-life psychosis in the anticipation hypothesis of schizophrenia.
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