Although conversion rates in the placebo group (34%, 10/29) were higher that those in the olanzapine group (16%, 5/31) after 1 year of active treatment, this difference did not reach statistical significance. 50 Thus, while results of both the PACE and PRIME studies support the short-term benefits of early treatment, prevention continues to be an open question. 41 RAP program naturalistic prospective study A very different approach has been adopted in the RAP program.
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