showed a trendP =0.078
They further demonstrated that this low-frequency haplotype showed a trend of association in a sample of unrelated schizophrenia cases and controls (661 cases, 2824 controls, P =0.078, OR=1.9) and was significant in a pooled sample of schizophrenia, schizoaffective, and bipolar disorder patients ( P =0.037, OR=1.9).