Long-term azithromycin therapy in patients with severe COPD and repeated exacerbations.

aeruginosa , a statistically significant reduction in AECOPD of 43.5% was observed, the number of hospitalizations fell by 47.1%, and their hospital stays by 32.5%, although these differences did not reach statistical significance.

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The subanalysis shows that Group 1, despite being the one with the highest number of AECOPD and hospitalizations prior to azithromycin therapy, demonstrated the greatest improvement with long-term azithromycin treatment, with highly significant reductions of around 70% in AECOPD and hospitalizations.

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