The B-Raf status of tumor cells may be a significant determinant of both antitumor and anti-angiogenic effects of pazopanib in xenograft tumor models.

Three days later, the 30 and 100 mg/kg doses induced 40% and 59% tumor growth inhibition, respectively (p = 0.030 (this p value represents a strong trend) and p = 0.002, respectively).

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