We have previously resolved CD4 + SP thymocytes into four subsets: SP1 (6C10 + CD69 + ), SP2 (6C10 - CD69 + ), SP3 (CD69 - Qa-2 - ), and SP4 (CD69 - Qa-2 + ), of which the proliferation, cytokine production, and survival capacities showed a trend of SP1<SP2<SP3<SP4.
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The molecular signature underlying the thymic migration and maturation of TCRαβ+ CD4+ CD8 thymocytes.
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