Alterations of serum biomarkers associated with lung ventilation function impairment in coal workers: a cross-sectional study.

Comparisons of lung ventilation functional parameters among CWP and control groups As shown in Figure 1 , when compared with the data from asymptomatic miners, most of the lung ventilation functional parameters were in a decreasing trend in patients with CWP.

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Correlations of lung ventilation functional parameters and levels of serum biomarkers in asymptomatic miners The results of Pearson's correlation analysis indicated that serum levels of IL-18 in the asymptomatic miners showed a trend towards positive association with all lung ventilation functional parameters; on the other hand, levels of IL-18R, sCD40, sCD40L, MMP-9, TIMP-9 and sICAM-1 showed a trend towards inverse association with all lung ventilation function parameters.

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