Improved vaccine protection against retrovirus infection after co-administration of adenoviral vectors encoding viral antigens and type I interferon subtypes.

After co-administration of vectors encoding IFNα9 or IFNβ, the mean viral loads in spleens of mice were also reduced more than 100-fold compared to unvaccinated or Env- and Gag-vaccinated mice, but the differences did not reach statistical significance ( P > 0.05).

also in 111,027 other papers