NK-like T cells and plasma cytokines, but not anti-viral serology, define immune fingerprints of resilience and mild disability in exceptional aging.

The impaired group also had higher mean and median values of IL-7, IL-10, TNF-α, CRP, and macrophage inhibitory protein-1β (MIP-1β), whereas the unimpaired group had higher mean/median values of IL-5; but these latter differences did not reach statistical significance.

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Whereas a significant cluster in factor analysis is generally defined by an Eigen value >1.0, we used a more stringent Eigen value ≥5.0 to identify principal components that were more highly significant.

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