Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer.

Quantification of ALDH+ area fraction confirmed a highly significant reduction in mice treated with the telomerase inhibitor as compared to controls (p < 0.001) (see additional file 2 , Supplementary figure 2G).

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A similar trend was also found for telomerase, although differences did not reach statistical significance.

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