Use of combination therapy was found to be associated with higher proportions of treatment success in univariable analysis compared to beta-lactam monotherapy [29/34 (85%) in combination versus 13/20 (65%) in monotherapy], however this did not reach statistical significance [odds ratio (OR) 3.1; 95% Confidence Interval (CI) 0.69–14.7, p = 0.1 for treatment success in patients that received combination therapy over those that received monotherapy].
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Impact of definitive therapy with beta-lactam monotherapy or combination with an aminoglycoside or a quinolone for Pseudomonas aeruginosa bacteremia.
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