Previous characterization of FIV proviral load in PBMC of co-infected and single infected cats showed a slight trend toward greater levels of provirus in FIV single infected cats with a significant difference between the groups at one of eight timepoints studied [ 26 ].
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Prior virus exposure alters the long-term landscape of viral replication during feline lentiviral infection.
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The three tissues with significant differences in IFNγ expression between co-infection and single infection (thymus, spleen and pre-scapular LN) were all lymphoid tissue, but there was a similar near-significant trend in the duodenum.