PcG complexes set the stage for epigenetic inheritance of gene silencing in early S phase before replication.

PLoS Genet · 2011 · PMC3207895 · PMID 22072989

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Interestingly, H3K9me3, also controlled by PcG proteins [28] , showed a trend similar to H3K27me3 ( Figure S2C ) during S phase, suggesting that PcG epigenetic signatures are inherited at the same time during replication.

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