The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis.

PLoS One · 2011 · PMC3210131 · PMID 22087248

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failed to reach statistical significanceno p-value reported

In our HCV-infected patients PNPLA3 148M/M homozygosity revealed an odds ratio of 1.666 for the risk of liver cancer ( table 4 ), which failed to reach statistical significance with our sample size.

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