A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial.

PLoS Med · 2011 · PMC3210754 · PMID 22087077

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did not reach statistical significanceno p-value reported

However, when looking at the individual sites, PCR-unadjusted efficacy of DHAPQ as compared to AL was significantly higher in Ndola (Zambia), Tororo (Uganda), and Nanoro (Burkina Faso), while at the other sites it was similar or the difference did not reach statistical significance ( Figure 4C ); for the comparison with ASAQ, DHAPQ performed significantly better at most sites, with the exception of Pamol and Afokang (Nigeria) ( Figure 4A ).

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of borderline significanceno p-value reported

Similarly, at this site the difference between DHAPQ and ASAQ PCR-adjusted efficacy was of borderline significance, though ASAQ efficacy was about 94%.

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