OCT2 was expressed in a much smaller proportion of tumours (5; 14%), all of which were either positive for SSX2-4 and SAGE1 or negative for both markers ( Figure 3B ); there was a negative trend between OCT2 and SSX2-4 expression, although this did not achieve formal statistical significance ( p = 0.08, Fisher's exact test).
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OCT2, SSX and SAGE1 reveal the phenotypic heterogeneity of spermatocytic seminoma reflecting distinct subpopulations of spermatogonia.
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