Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness.

PLoS Genet · 2011 · PMC3213169 · PMID 22102826

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closest p · 1.6× alpha

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nearly significantp = 0.08so close (0.05 < p ≤ 0.1)

We also investigated the same genotypes in stage 11 embryos when only the stripe 2 enhancer was deleted from the native eve locus ( eve ΔMSE / R13) and again found a significant reduction of parasegment 3 in MSE ( p<0.01 , the Mann-Whitney Wilcoxon ranksum test was used here and in all subsequent statistical testing) and nearly significant ( p = 0.08 ) in INV_MSE hemizygotes ( Figure S7 ; Table S4 ).

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