Adipokines, insulin resistance, metabolic syndrome, and breast cancer recurrence: a cohort study.

Breast Cancer Res · 2011 · PMC3219197 · PMID 21450081

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a decreasing trendno p-value reported

an increasing trendno p-value reported

HOMA-IR showed an increasing trend with borderline significance in the ER/PR-negative group ( P for trend = 0.087 in model 1 and 0.114 in model 2) and a decreasing trend in the ER/PR-positive group ( P for trend = 0.081 in model 1 and 0.072 in model 2).

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borderline significanceno p-value reported

HOMA-IR values showed a positive trend with borderline significance in the ER/PR-negative group ( P- value for trend = 0.078), whereas insulin levels did not ( P- value for trend = 0.450).

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a negative trendno p-value reported

a positive trendno p-value reported

Homeostasis model assessment for insulin resistance (HOMA-IR) showed a positive trend for recurrence in the ER/PR-negative group ( P for trend = 0.087) and a negative trend in the ER/PR-positive group ( P for trend = 0.081).

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marginally significantno p-value reported

Unexpectedly, an inverse, marginally significant association between insulin resistance and cancer recurrence was observed in the ER/PR-positive group; this trend was also observed in the analyses of serum insulin levels.

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