Impact of de-escalation therapy on clinical outcomes for intensive care unit-acquired pneumonia.

Although there was a lower trend for the pneumonia-related mortality rate in the de-escalation group, the difference did not reach statistical significance by day 14 after the diagnosis of ICU-acquired pneumonia (1 (2.3%) of 44 patients versus 10 (10.8%) of 93 patients; P = 0.08) (Figure 1 ).

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