Exogenous glucagon-like peptide-1 attenuates the glycaemic response to postpyloric nutrient infusion in critically ill patients with type-2 diabetes.

Crit Care · 2011 · PMC3222072 · PMID 21255422

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0.0600

closest p · 1.2× alpha

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a strong trendP = 0.06so close (0.05 < p ≤ 0.1)

There was a strong trend for lower glucagon concentrations on the day of GLP-1 administration, including baseline (at t = 0 minutes: GLP-1: 181 ± 24 vs. placebo: 219 ± 29 pmol/l; P = 0.06, at t = 30 minutes: GLP-1: 175 ± 21 vs. placebo: 214 ± 29: P = 0.06, and at t = 270 minutes: GLP-1: 184 ± 32 vs. placebo: 212 ± 39; P = 0.11) so that plasma glucagon was lower on the day of GLP-1 (AUC 0-270 minutes ; P < 0.01).

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