Mutations in the ELANE gene are associated with development of periodontitis in patients with severe congenital neutropenia.

J Clin Immunol · 2011 · PMC3223588 · PMID 21796505

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did not reach statistical significanceno p-value reported

In addition, the mean and median levels of IL-17, IL-6, and TNF-α in patients with ELANE mutations were higher than in HAX1 or unknown mutations although these differences did not reach statistical significance, most likely due to the small size of the cohort and great variations within groups.

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