Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus.

The number of genetically divergent high-frequency haplotypes showed a trend of balanced diversity (Figure 2 ).

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The observed surplus of mid- and high-frequency haplotypes at the IL-4Rα locus has generated highly significant D and H values that are more extreme than those observed by other studies of disease-associated chicken genes [ 6 , 48 ] – however, D and H are likely to be affected by demographic aspects of chicken history and the samples pooling [ 66 ].

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