Barely Significant
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Alterations in the interleukin-1/interleukin-1 receptor antagonist balance modulate cardiac remodeling following myocardial infarction in the mouse.

PLoS One · 2011 · PMC3225370 · PMID 22140485

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We noticed a small increase in cardiac rupture in IL-1Ra-/- mice but it did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.