Barely Significant
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Safety and effectiveness of adalimumab in a clinical setting that reflects Canadian standard of care for the treatment of rheumatoid arthritis (RA): results from the CanACT study.

BMC Musculoskelet Disord · 2011 · PMC3226526 · PMID 22093579

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a clear trendno p-value reported
When patients were classified according to prior experience with a BDMARD, a clear trend in clinical responses was observed: patients naïve to BDMARD therapy typically demonstrated greater clinical effectiveness when compared with patients who had experienced prior BDMARD therapy, despite comparable baseline disease characteristics (data not shown).

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