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Amygdala-prefrontal pathways and the dopamine system affect nociceptive responses in the prefrontal cortex.

BMC Neurosci · 2011 · PMC3228703 · PMID 22085449

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The duration of nociceptive responses tended to increase in DA-depleted animals, but the difference versus the pre-HFS control value did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.