Next-generation DNA sequencing-based assay for measuring allelic expression imbalance (AEI) of candidate neuropsychiatric disorder genes in human brain.

Furthermore, with the exception of MAPT [ 26 ], no genes previously demonstrated to exhibit AEI in human cerebral cortex in PCR-based AEI assays, including DTNBP1 [ 22 ], COMT [ 23 ], GNB1L [ 50 ], TBX1 [ 50 ], OPRM1 [ 28 ], DRD2 [ 29 ], and CHRNA5 [ 33 ] were included in the list of nominally significant cis SNP-transcript pairs.

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