Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data.

PLoS One · 2011 · PMC3229530 · PMID 22164237

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did not reach statistical significanceno p-value reported

These reports were supported by a FDA meta-analysis of RCTs, which found that the risk of all-cause and cardiovascular mortality and MI tended to be lower with pioglitazone and higher with rosiglitazone (although most results did not reach statistical significance) [4] .

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