Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy.

As expected [17] , the proportions of Tregs defined that way were lower in both subject groups than if defined as PCH101 + only (1.6% in untreated patients versus 1% in controls), but differences between groups showed similar trends, although they did not reach statistical significance (p = 0.14).

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