Adenosine A(2A) Receptor Antagonists Do Not Disrupt Rodent Prepulse Inhibition: An Improved Side Effect Profile in the Treatment of Parkinson's Disease.

Parkinsons Dis · 2012 · PMC3236485 · PMID 22191072

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0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

marginally significantP = 0.06so close (0.05 < p ≤ 0.1)

For L-dopa ( Figure 2(f) ), a one-way ANOVA revealed only a marginally significant effect on PPI overall ( F (4, 35) = 2.46, P = 0.06).

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approached significanceP = 0.06so close (0.05 < p ≤ 0.1)

L-dopa significantly reduced haloperidol-induced catalepsy ( F (5, 50) = 7.13, P < 0.01) at 100 mg/kg, whereas 300 mg/kg approached significance ( P = 0.06) compared to vehicle + haloperidol treatment ( Figure 1(f) ). 3.2.

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marginal significanceP = 0.06so close (0.05 < p ≤ 0.1)

Ropinirole reduced time cataleptic ( F (5, 30) = 11.42, P < 0.01) at 10 mg/kg, whereas 1 and 3 mg/kg showed marginal significance ( P = 0.06) compared to vehicle + haloperidol treatment ( Figure 1(e) ).

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