The association signal was almost entirely due to a decreased frequency of the rs2530547C-rs324981A-rs727162C haplotype among UC patients (OR = 0.73; P = 0.0059), while a similar trend was observed among CD patients, although this did not reach statistical significance (OR = 0.83; P = 0.11).
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Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).
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